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ICMT-IN-48

ICMT-IN-48 (compound 1) is an ICMT inhibitor that is competitive (Km=13 μM) for the prenylated methyl acceptor, the first substrate of ICMT. ICMT-IN-48 inhibits ICMT activity with IC50s affected by the concentration of the second substrate S-adenosylmethinine (SAM), and the IC50s are 3.5 μM (1×Km SAM) and 2.3 μM (10×Km SAM), respectively.

For research use only. We do not sell to patients.

  • CAS No.: 337486-54-1
  • Formula: C30H37NO5
  • Molecular Weight:491.62
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • ICMT-IN-48 Chemical Structure
    ICMT-IN-48 Chemical Structure
CAS No.: 337486-54-1
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  • ICMT-IN-48 Chemical Structure
    ICMT-IN-48 Chemical Structure
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  • ICMT-IN-48