G3-C12
Based on 1 publication(s) in Google Scholar
G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
For research use only. We do not sell to patients.
- Purity: 99.64%
- CAS No.: 848301-94-0
- Formula: C74H115N23O23S2
- Molecular Weight:1758.98
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) G3-C12
MoreAll Galectin Isoforms
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Biological Activity
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Galectin-3 |
G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 848301-94-0
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Appearance Solid
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Molecular Weight 1758.98
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Formula C74H115N23O23S2
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Color White to off-white
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Sequence
Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg
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Sequence Shortening
ANTPCGPYTHDCPVKR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Transl Med
Myeloid leukemia-derived galectin-1 downregulates CAR expression to hinder cytotoxicity of CAR T cells. [Abstract]2024 Jan 6;22(1):32. PMID: 38184596
Solvent & Solubility
H2O : ≥ 100 mg/mL (56.85 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.5685 mL | 2.8426 mL | 5.6851 mL | 14.2128 mL |
| 5 mM | 0.1137 mL | 0.5685 mL | 1.1370 mL | 2.8426 mL | |
| 10 mM | 0.0569 mL | 0.2843 mL | 0.5685 mL | 1.4213 mL | |
| 15 mM | 0.0379 mL | 0.1895 mL | 0.3790 mL | 0.9475 mL | |
| 20 mM | 0.0284 mL | 0.1421 mL | 0.2843 mL | 0.7106 mL | |
| 25 mM | 0.0227 mL | 0.1137 mL | 0.2274 mL | 0.5685 mL | |
| 30 mM | 0.0190 mL | 0.0948 mL | 0.1895 mL | 0.4738 mL | |
| 40 mM | 0.0142 mL | 0.0711 mL | 0.1421 mL | 0.3553 mL | |
| 50 mM | 0.0114 mL | 0.0569 mL | 0.1137 mL | 0.2843 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
G3-C12 Related Classifications
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