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Cat. No.: HY-114635

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Dexecadotril

(Synonyms: Retorphan)

Dexecadotril (Retorphan) is a powerful and selective neprilysin (NEP) inhibitor. Dexecadotril is a prodrug of the R-enantiomers of Thiorphan (HY-W013375). Dexecadotril shows intestinal antisecretatory action.

For research use only. We do not sell to patients.

CAS No.: 112573-72-5
Formula: C₂₁H₂₃NO₄S
Molecular Weight:385.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Dexecadotril Chemical Structure

CAS No.: 112573-72-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 112573-72-5
Molecular Weight 385.48
Formula C₂₁H₂₃NO₄S
SMILES

O=C(OCC1=CC=CC=C1)CNC([C@H](CSC(C)=O)CC2=CC=CC=C2)=O
Synonyms

Retorphan
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thierry Monteil, et al. Strategies for access to enantiomerically pure ecadotril, dexecadotril and fasidotril: a review. Mini Rev Med Chem. 2002 Jun;2(3):209-17. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dexecadotril

Sacubitril

Thiorphan

Sacubitrilat

Racecadotril

Sacubitril hemicalcium salt

Phenylalanylalanine

Candoxatril

Kelatorphan

Sacubitril (Standard)

Racecadotril (Standard)

Phenylalanylalanine (Standard)

Sacubitrilat (Standard)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dexecadotril

Sacubitril

Thiorphan

Sacubitrilat

Racecadotril

Sacubitril hemicalcium salt

Phenylalanylalanine

Candoxatril

Kelatorphan

Sacubitril (Standard)

Racecadotril (Standard)

Phenylalanylalanine (Standard)

Sacubitrilat (Standard)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dexecadotril Related Classifications

HY-114635 Related Classifications