Gap43 - growth associated protein 43 Gene

Also Known as B-50; Basp2; GAP-43

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14432

Summary

Predicted to enable Calmodulin binding activity and phospholipid binding activity. Acts upstream of or within axon choice point recognition; cell fate commitment; and glial cell differentiation. Located in several cellular components, including axon; plasma membrane; and postsynaptic density. Is expressed in several structures, including alimentary system; future brain; genitourinary system; nervous system; and sensory organ. Orthologous to human GAP43 (growth associated protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Gap43 Products (1)

mRNA Protein Name
NM_008083.2 NP_032109.1 neuromodulin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23462742 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within astrocyte differentiation IMP
IMP: Inferred from mutant phenotype
15234344 MGI
acts upstream of or within axon choice point recognition IMP
IMP: Inferred from mutant phenotype
7859286 MGI
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
10662636 MGI
acts upstream of or within cell fate commitment IMP
IMP: Inferred from mutant phenotype
15234344 MGI
acts upstream of or within radial glial cell differentiation IMP
IMP: Inferred from mutant phenotype
15234344 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
10482234 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
21752992 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
24582971 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16892058 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuromodulin

  • axonal membrane protein GAP-43

  • brain abundant, membrane attached signal protein 2

  • calmodulin-binding protein P-57

  • growth accentuating protein 43

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-129108 9-cis-UAB30 / Unkown
HY-161783 HDAC6-IN-45 / Unkown
HY-168857 GSK-3β inhibitor 24 / Unkown
HY-RS05272 GAP43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18821 Gap43 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25311 Gap43 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gap43 NCBI NCBI:2596