Complement Component 3a
Complement component 3a is the anaphylatoxin released from the N-terminal region of the C3 alpha chain when C3 convertases of any activation pathway cleave C3. This small cationic peptide signals through the G protein-coupled receptor C3aR, which is expressed on mast cells, eosinophils, monocytes, and other immune cells. C3a triggers mediator release, smooth-muscle contraction, chemotaxis, and amplification of the inflammatory response, and it modulates adaptive immunity and regeneration processes. C3a is rapidly inactivated by carboxypeptidase cleavage to C3adesArg. Recombinant C3a supports receptor-binding assays, anaphylatoxin signaling studies, and complement-inflammation research. Compared with C5a, C3a is a weaker but broadly acting inflammatory mediator.
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Complement Component 3a Recombinant Proteins (4)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
