IDO1-IN-11
IDO1-IN-11 is an IDO1 inhibitor with an IC50 value of 0.6 nM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2306411-34-5
- Fòrmula: C22H17ClFN3O3
- Peso molecular:425.84
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
3.2 nM
Compound: 13
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Inhibition of heme binding to IDO1 in interferon-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine production using L-tryptophan as substrate incubated for 48 hrs by fluorescence based assay
Inhibition of heme binding to IDO1 in interferon-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine production using L-tryptophan as substrate incubated for 48 hrs by fluorescence based assay
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[PMID: 32292563] |
Chemical Information
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No. CAS 2306411-34-5
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Peso molecular 425.84
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Fòrmula C22H17ClFN3O3
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SMILES
O=C(C1=CC(Cl)=CC=C1)NC2=CN=C(C3(COC3)C(NC4=CC=C(C=C4)F)=O)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1-IN-11 Related Classifications
HY-145332 Related Classifications
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