IDO1-IN-11
IDO1-IN-11 is an IDO1 inhibitor with an IC50 value of 0.6 nM.
For research use only. We do not sell to patients.
- CAS No.: 2306411-34-5
- Formula: C22H17ClFN3O3
- Molecular Weight:425.84
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
3.2 nM
Compound: 13
|
Inhibition of heme binding to IDO1 in interferon-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine production using L-tryptophan as substrate incubated for 48 hrs by fluorescence based assay
Inhibition of heme binding to IDO1 in interferon-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine production using L-tryptophan as substrate incubated for 48 hrs by fluorescence based assay
|
[PMID: 32292563] |
Chemical Information
-
CAS No. 2306411-34-5
-
Molecular Weight 425.84
-
Formula C22H17ClFN3O3
-
SMILES
O=C(C1=CC(Cl)=CC=C1)NC2=CN=C(C3(COC3)C(NC4=CC=C(C=C4)F)=O)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)