IDO1-IN-13
IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. IDO1-IN-13 has cellular IDO1 inhibition (HeLa EC50= 30 nM). IDO1-IN-13 decreases 51% of the kyn/trp ratio in SK-OV-3 xenograft tumor tissues.
For research use only. We do not sell to patients.
- Formula: C20H16BrN5O2S
- Molecular Weight:470.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IDO1 30 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Detroit 551 | CC50 |
>10 μM
Compound: 27a
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Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
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[PMID: 34929581] |
Chemical Information
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Molecular Weight 470.34
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Formula C20H16BrN5O2S
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SMILES
N#CC1=CC=C(C=C1)NC(NCC2=CSC(/C(NC3=CC=CC(Br)=C3)=N/O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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