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Cat. No.: HY-184993

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IDO1 ligand-2

IDO1 ligand-2 (Compound 6) is a IDO1 ligand that can be used for the synthesis of PROTACs, such as NU223612 (HY-151886).

For research use only. We do not sell to patients.

CAS No.: 2872618-03-4
Formula: C₂₉H₃₄FN₃O₂
Molecular Weight:475.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

IDO1 ligand-2 Chemical Structure

CAS No.: 2872618-03-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IDO1 ligand-2 (Compound 6) is a IDO1 ligand that can be used for the synthesis of PROTACs, such as NU223612 (HY-151886)^[1].

IC₅₀ & Target^[1]

IDO1

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms :

Chemical Information

CAS No. 2872618-03-4
Molecular Weight 475.60
Formula C₂₉H₃₄FN₃O₂
SMILES

O=C([C@H](C)[C@@]1([H])CC[C@](C2=CC=NC3=CC=C(F)C=C23)([H])CC1)NC4=CC=C(OC5CCNCC5)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bollu LR, et al. Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma. Journal of medicinal chemistry. 2022 Dec 08;65(23):15642-15662. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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IDO1 ligand-2

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

IDO1 ligand-2 Related Classifications

HY-184993 Related Classifications