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Cat. No.: HY-146673

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IDO1/TDO-IN-2

IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC₅₀s of 0.1 and 0.07 μM. IDO1/TDO-IN-2 has the potential for the research of cancer diseases.

For research use only. We do not sell to patients.

CAS No.: 5466-47-7
Formula: C₁₆H₉N₃O₂
Molecular Weight:275.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

IDO1/TDO-IN-2 Chemical Structure

CAS No.: 5466-47-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC₅₀s of 0.1 and 0.07 μM. IDO1/TDO-IN-2 has the potential for the research of cancer diseases^[1].

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms :

Chemical Information

CAS No. 5466-47-7
Molecular Weight 275.26
Formula C₁₆H₉N₃O₂
SMILES

O=C1C2=CC=CC=C2C(C3=C1N=NN3C4=CC=CC=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO). Eur J Med Chem. 202 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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IDO1/TDO-IN-2

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

IDO1/TDO-IN-2 Related Classifications

HY-146673 Related Classifications