Imidacloprid-urea
Based on 1 Customer Validation
Imidacloprid-urea is a metabolite of Imidacloprid (HY-B0838). Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.86%
- CAS No.: 120868-66-8
- 화학식: C9H10ClN3O
- 분자량:211.65
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
Chemical Information
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CAS No. 120868-66-8
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Appearance Solid
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분자량 211.65
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화학식 C9H10ClN3O
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Color Off-white to light yellow
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SMILES
O=C1NCCN1CC2=CC=C(Cl)N=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 125 mg/mL (590.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 12.5 mg/mL (59.06 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
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Protocol for Pharmacokinetic Study
Pharmacokinetic studies quantify how an organism handles a drug over time through absorption, distribution, metabolism, and excretion, and the core experimental readout is the concentration-time profile of parent drug and, when relevant, metabolites in biological matrices such as plasma, whole blood, urine, bile, or tissue. Pharmacokinetic analysis links dose, route, exposure, clearance, half-life, distribution, bioavailability, and systemic exposure to drug efficacy and toxicity hypotheses rather than measuring a signaling pathway directly. The literature links pharmacokinetics to drug-development phenotypes by showing that drug metabolism and pharmacokinetics influence compound progression, exposure-response interpretation, safety margins, dosing strategy, and failure risk during discovery and development. DMPK science contributes to compound optimization by integrating physicochemical properties, in vitro metabolism, transporter behavior, in vivo exposure, and pharmacodynamic contex
순도&문서
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 4.7248 mL | 23.6239 mL | 47.2478 mL | 118.1195 mL |
| 5 mM | 0.9450 mL | 4.7248 mL | 9.4496 mL | 23.6239 mL | |
| 10 mM | 0.4725 mL | 2.3624 mL | 4.7248 mL | 11.8120 mL | |
| 15 mM | 0.3150 mL | 1.5749 mL | 3.1499 mL | 7.8746 mL | |
| 20 mM | 0.2362 mL | 1.1812 mL | 2.3624 mL | 5.9060 mL | |
| 25 mM | 0.1890 mL | 0.9450 mL | 1.8899 mL | 4.7248 mL | |
| 30 mM | 0.1575 mL | 0.7875 mL | 1.5749 mL | 3.9373 mL | |
| 40 mM | 0.1181 mL | 0.5906 mL | 1.1812 mL | 2.9530 mL | |
| 50 mM | 0.0945 mL | 0.4725 mL | 0.9450 mL | 2.3624 mL | |
| DMSO | 60 mM | 0.0787 mL | 0.3937 mL | 0.7875 mL | 1.9687 mL |
| 80 mM | 0.0591 mL | 0.2953 mL | 0.5906 mL | 1.4765 mL | |
| 100 mM | 0.0472 mL | 0.2362 mL | 0.4725 mL | 1.1812 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.