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Cat. No.: HY-150255

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IMP2-IN-3

IMP2-IN-3 is a potent IMP2 inhibitor. IMP2-IN-3 shows anticancer effects.

For research use only. We do not sell to patients.

CAS No.: 1448353-63-6
Formula: C₂₃H₂₂Cl₂N₂O₃S
Molecular Weight:477.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

IMP2-IN-3 Chemical Structure

CAS No.: 1448353-63-6

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Sample (0.1mg)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

IMP2-IN-3 is a potent IMP2 inhibitor. IMP2-IN-3 shows anticancer effects^[1].

In Vitro

IMP2-IN-3 (compound 9; 50 μM; 96 hours) inhibits the cell growth of Huh7 cells, it does not affect the viability of differentiated Huh7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Huh7 cells
Concentration:

50 μM
Incubation Time:

96 hours
Result:

Inhibited the cell growth of Huh7 cells.

Chemical Information

CAS No. 1448353-63-6
Molecular Weight 477.40
Formula C₂₃H₂₂Cl₂N₂O₃S
SMILES

O=C(C1=C(NC(N(CCC)CCC2=CC=CC=C2)=O)C=C(C3=CC(Cl)=C(Cl)C=C3)S1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Charlotte Dahlem, et al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17(2):361-375. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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