CB-64D
CB-64D is the agonist for sigma receptor 2 and sigma receptor 1 with Ki of 16.5 and 3063 nM. CB-64D induces apoptosis in cancer cell SK-N-SH.
For research use only. We do not sell to patients.
- CAS No.: 157752-20-0
- Formula: C22H23NO2
- Molecular Weight:333.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Sigma Receptor Isoforms
More
Biological Activity
|
Sigma 2 Receptor 16.5 nM (Ki) |
Sigma 1 Receptor 3063 nM (Ki) |
Chemical Information
-
CAS No. 157752-20-0
-
Molecular Weight 333.42
-
Formula C22H23NO2
-
SMILES
O=C1C[C@@]2(C3=CC=CC(O)=C3)CCN(C)[C@@](C2)([H])/C1=C\C4=CC=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nicholson H, et al., Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity. J Pharmacol Exp Ther. 2015 Aug;354(2):203-12. [Content Brief]
[2]. Bowen WD, et al., CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity. Eur J Pharmacol. 1995 May 24;278(3):257-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB-64D Related Classifications
HY-120360 Related Classifications
Powered by Bioz