IQB-782
IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity.
For research use only. We do not sell to patients.
- CAS No.: 40454-21-5
- Formula: C4H9N3O2S
- Molecular Weight:163.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ki (app): 0.14 μM (TAFI)[1]
IQB-782 inhibits TAFI related carboxypeptidases with IC50s of 49 μM and 12 μM for CPN and CPB, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40454-21-5
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Molecular Weight 163.20
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Formula C4H9N3O2S
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SMILES
N=C(N)N[C@@H](CS)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71. [Content Brief]
[2]. Moratalla R, et al. Pharmacological study of the new mucolytic drug N-guanyl-cysteine. Arzneimittelforschung. 1986 Jun;36(6):918-23. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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