IRAK4-IN-34
IRAK4-IN-34 (compound 19) is a potent, selective, and orally active Interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 of 0.73 nM. IRAK4-IN-34 exhibits good selectivity vs both hERG and other kinases. IRAK4-IN-34 shows favorable in vivo PK properties. IRAK4-IN-34 can be used for inflammatory diseases research.
For research use only. We do not sell to patients.
- CAS No.: 2411498-83-2
- Formula: C28H29N9O2S
- Molecular Weight:555.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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IRAK4 0.73 nM (IC50) |
Chemical Information
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CAS No. 2411498-83-2
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Molecular Weight 555.65
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Formula C28H29N9O2S
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SMILES
N#CC1=CC2=CC=C(C3=NC=C(C(NC4(COC4)C)=C3)C5=NN=C(S5)N6C[C@@H]7CC[C@H](C6)[C@H]7NC(C)=O)N2N=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)