1. Metabolic Enzyme/Protease
  2. Liposome
  3. iso-A11B5C1

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery.

For research use only. We do not sell to patients.

iso-A11B5C1

iso-A11B5C1 Chemical Structure

CAS No. : 3063868-70-9

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Description

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery[1].

In Vitro

iso-A11B5C1 LNP​ exhibits significant luciferase expression levels in HeLa cells after encapsulating Firefly Luciferase mRNA (HY-174790)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

iso-A11B5C1 LNP (i.m.) exhibits high mRNA expression in the muscle region and induces a strong humoral and cellular immune response in mice, suggesting its potential as an mRNA vaccine vector[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

662.08

Formula

C41H79N3O3

CAS No.
SMILES

CCCCCC(C)CCC(OCCCCCC(NCCN1CCCC1)C(NCCCCCCCC/C=C\CCCCCCCC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
iso-A11B5C1
Cat. No.:
HY-170896
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