Isoglobotriaose
Based on 1 Customer Validation
Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of Globotriaose, the ganglioside derivatives of them locate in difference position of small intestine, isoglobotriaosylceramide is restricted to the nonepithelial residue, while globotriaosylceramide is in both compartments.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 41744-59-6
- Formula: C18H32O16
- Molecular Weight:504.44
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Isoglobotriaose is synthesized from lactose, glucose-1-phophate (Glc-1-P), and uridine 5’-triphosphate (UTP) by a one-pot three-enzyme system containing UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and an α1-3galactosytransferase (α1-3GalT)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 41744-59-6
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Appearance Solid
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Molecular Weight 504.44
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Formula C18H32O16
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Color White to off-white
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SMILES
O[C@@H]([C@@H](O[C@@H]([C@@H]1O)CO)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)[C@H]1O[C@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO
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Synonyms
Gala-3Galb-4Glc
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Structure Classification
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Initial Source
Escherichia coli
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 100 mg/mL (198.24 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Li W, et al. Strategies for chemoenzymatic synthesis of carbohydrates. Carbohydr Res. 2019 Jan 15;472:86-97. [Content Brief]
[2]. Breimer ME, et al. Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine. J Biol Chem. 1982 Jan 10;257(1):557-68. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.9824 mL | 9.9120 mL | 19.8240 mL | 49.5599 mL |
| 5 mM | 0.3965 mL | 1.9824 mL | 3.9648 mL | 9.9120 mL | |
| 10 mM | 0.1982 mL | 0.9912 mL | 1.9824 mL | 4.9560 mL | |
| 15 mM | 0.1322 mL | 0.6608 mL | 1.3216 mL | 3.3040 mL | |
| 20 mM | 0.0991 mL | 0.4956 mL | 0.9912 mL | 2.4780 mL | |
| 25 mM | 0.0793 mL | 0.3965 mL | 0.7930 mL | 1.9824 mL | |
| 30 mM | 0.0661 mL | 0.3304 mL | 0.6608 mL | 1.6520 mL | |
| 40 mM | 0.0496 mL | 0.2478 mL | 0.4956 mL | 1.2390 mL | |
| 50 mM | 0.0396 mL | 0.1982 mL | 0.3965 mL | 0.9912 mL | |
| 60 mM | 0.0330 mL | 0.1652 mL | 0.3304 mL | 0.8260 mL | |
| 80 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6195 mL | |
| 100 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4956 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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