Isoguvacine
Based on 2 publication(s) in Google Scholar
For research use only. We do not sell to patients.
- CAS No.: 64603-90-3
- Formula: C6H9NO2
- Molecular Weight:127.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Isoguvacine
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Biological Activity
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
67 μM
Compound: 2, IGU
|
Agonist activity at human GABAC rho 1 receptor expressed in HEK293 cells by FMP assay
Agonist activity at human GABAC rho 1 receptor expressed in HEK293 cells by FMP assay
|
[PMID: 17655213] |
| Oocyte | EC50 |
160 μM
Compound: 4
|
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes
|
[PMID: 11412984] |
| Oocyte | EC50 |
50 μM
Compound: 4
|
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes
|
[PMID: 11412984] |
| Oocyte | EC50 |
55 μM
Compound: 4
|
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
|
[PMID: 11412984] |
| Oocyte | EC50 |
75 μM
Compound: 4
|
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes
|
[PMID: 11412984] |
Chemical Information
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CAS No. 64603-90-3
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Molecular Weight 127.14
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Formula C6H9NO2
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SMILES
O=C(O)C1=CCNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Eur J Pharmacol
Loop diuretics mitigate juvenile immobilization treatment-induced hippocampal dysfunction. [Abstract]2025 Jun 5:996:177447. PMID: 40023355 -
J Neurochem
The GABAergic pathway from anterior cingulate cortex to lateral hypothalamus area regulates irritable bowel syndrome in mice and its underlying mechanism. [Abstract]2024 Sep;168(9):2814-2831. PMID: 38877776
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)