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Cat. No.: HY-108880A

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Carindacillin

Name: Carindacillin
Brand: MedChemExpress
SKU: HY-108880A
Availability: PreOrder

(Synonyms: Indanyl carbenicillin; CP-15464-2 free base)

Carindacillin (Indanyl carbenicillin; CP-15464-2 free base) is an orally active prodrug of Carbenicillin (HY-B0525). Carindacillin undergoes intestinal uptake via a proton gradient-driven carrier-mediated pathway and is rapidly hydrolyzed in vivo to release the bioactive Carbenicillin, which interferes with cell wall synthesis by inhibiting bacterial penicillin-binding proteins. Carindacillin can be used in research related to bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 35531-88-5
Formula: C₂₆H₂₆N₂O₆S
Molecular Weight:494.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Carindacillin Chemical Structure

CAS No.: 35531-88-5

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Carindacillin (CIPC) is actively transported into rat intestinal BBMV primarily via the monocarboxylic acid transport system, with a K_m of 0.54 mM, a K_i of 0.59 mM, and an apparent uptake clearance of 499 × 10^-3 µl/mg protein per s^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 35531-88-5
Molecular Weight 494.56
Formula C₂₆H₂₆N₂O₆S
SMILES

O=C(OC1=CC=C(CCC2)C2=C1)C(C3=CC=CC=C3)C(N[C@H]4[C@]5([H])N(C4=O)[C@H](C(C)(S5)C)C(O)=O)=O
Synonyms

Indanyl carbenicillin; CP-15464-2 free base
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li YH, et al. Role of the monocarboxylic acid transport system in the intestinal absorption of an orally active beta-lactam prodrug: carindacillin as a model. International journal of pharmaceutics. 1999 Nov 30;191(2):151-9.

[2]. Michiels HG, et al. The treatment of chronic pyelonephritis with carindacillin. Current medical research and opinion. 1978;5(5):394-400.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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