CP-615003
CP-615003 is a potent and subtype-selective partial agonist of GABAA receptor (GABAA receptor) (Ki = 1.1 μM). CP-615003 is mainly converted into the active metabolite CP-900725 through oxidative deamination in monkeys and humans, and the latter also has GABAA receptor affinity. CP-615003 is a substrate of P-glycoprotein (P-gp/MDR1), resulting in severe limitation of its penetration into the central nervous system (CNS). CP-615003 can be used for the study of CNS-related indications.
For research use only. We do not sell to patients.
- CAS No.: 329016-45-7
- Formula: C20H24FN3O3
- Molecular Weight:373.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 329016-45-7
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Molecular Weight 373.42
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Formula C20H24FN3O3
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SMILES
O=C(C1=CNC2=C1C(CCC2)=O)NC3=CC=C(C(F)=C3)OCCNCCC
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Synonyms
NGD-913
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-615003 Related Classifications
HY-165444 Related Classifications
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Keywords
- CP-615003
- 329016-45-7
- NGD-913
- CP615003
- CP 615003
- NGD913
- NGD 913
- GABA Receptor
- Gamma-aminobutyric acid Receptor
- γ-Aminobutyric acid Receptor
- P-glycoprotein (P-gp)
- CNS penetration
- cerebrospinal fluid (CSF)
- brain extracellular fluid (ECF)
- multidrug resistance protein 1 (MDR1)
- pharmacokinetics
- receptor occupancy projection
- Inhibitor
- inhibitor
- inhibit