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Domvanalimab

(Synonyms: AB154)
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Based on 1 Customer Validation

Domvanalimab (AB154) is an anti-TIGIT humanized monoclonal antibody. Domvanalimab binds human TIGIT9 and blocks the TIGIT-CD155 interaction. Domvanalimab can be used for studies of non-small cell lung cancer and esophageal cancer.

For research use only. We do not sell to patients.

  • Purity : 98.62%
  • CAS No.: 2368219-35-4
  • Molecular Weight:145.12 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Domvanalimab
  • Experimental Validation Results for Domvanalimab
  • Experimental Validation Results for Domvanalimab
  • Domvanalimab Chemical Structure
    Domvanalimab Chemical Structure
CAS No.: 2368219-35-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Domvanalimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1X106 A549 cells with Domvanalimab (HY-P99858, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized Human TIGIT Protein (ECD, His Tag) can bind Domvanalimab. The EC50 for this effect is 1.51 ng/mL.

  • Domvanalimab Chemical Structure
    1/16
  • Domvanalimab
  • Flow cytometric analysis of 1X106 A549 cells with Domvanalimab (HY-P99858, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized Human TIGIT Protein (ECD, His Tag) can bind Domvanalimab. The EC50 for this effect is 1.51 ng/mL.