Fmoc-MMAE
Based on 1 Customer Validation
Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC.
For research use only. We do not sell to patients.
- Purity: 99.35%
- CAS No.: 474645-26-6
- Formula: C54H77N5O9
- Molecular Weight:940.22
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Storage:
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Auristatin |
Fmoc-MMAE is a protective group-conjugated Monomethyl auristatin E (HY-15162).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 474645-26-6
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Appearance Solid
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Molecular Weight 940.22
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Formula C54H77N5O9
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : ≥ 45 mg/mL (47.86 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.0636 mL | 5.3179 mL | 10.6358 mL | 26.5895 mL |
| 5 mM | 0.2127 mL | 1.0636 mL | 2.1272 mL | 5.3179 mL | |
| 10 mM | 0.1064 mL | 0.5318 mL | 1.0636 mL | 2.6590 mL | |
| 15 mM | 0.0709 mL | 0.3545 mL | 0.7091 mL | 1.7726 mL | |
| 20 mM | 0.0532 mL | 0.2659 mL | 0.5318 mL | 1.3295 mL | |
| 25 mM | 0.0425 mL | 0.2127 mL | 0.4254 mL | 1.0636 mL | |
| 30 mM | 0.0355 mL | 0.1773 mL | 0.3545 mL | 0.8863 mL | |
| 40 mM | 0.0266 mL | 0.1329 mL | 0.2659 mL | 0.6647 mL |
Fmoc-MMAE Related Classifications
HY-78933 Related Classifications
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