Gostatin
Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism.
For research use only. We do not sell to patients.
- CAS No.: 78416-84-9
- Formula: C8H10N2O5
- Molecular Weight:214.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 78416-84-9
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Molecular Weight 214.18
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Formula C8H10N2O5
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SMILES
OC(CC1=C(NCC(C1=O)N)C(O)=O)=O
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Synonyms
Gostatine
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Structure Classification
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Initial Source
Streptomyces sumanensis nov. sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)