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LM-4108

(Synonyms: N-(2-Phenylethyl)-indomethacin amide)

LM-4108 (N-(2-Phenylethyl)-indomethacin amide) is a selective and orally active COX-2 inhibitor with an IC50 of 0.06 μM for purified human COX-2. LM-4108 shows anti-inflammatory activity and may be effective in prevention of cancer. Half-lives for the disappearance of 10 μM LM-4108 in rat, human, and mouse liver microsomes were 11 min, 21 min, and 51 min, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 261766-32-9
  • Formula: C27H25ClN2O3
  • Molecular Weight:460.95
  • Storage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • LM-4108 Chemical Structure
    LM-4108 Chemical Structure
CAS No.: 261766-32-9
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100 mg

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    LM-4108 Chemical Structure
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  • LM-4108