NH2-C2-NH-Boc
Based on 1 Customer Validation
NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.41%
- CAS No.: 57260-73-8
- Formula: C7H16N2O2
- Molecular Weight:160.21
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57260-73-8
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Appearance Liquid (Density: 1.012 g/cm3)
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Molecular Weight 160.21
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Formula C7H16N2O2
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Color Colorless to light yellow
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SMILES
O=C(NCCN)OC(C)(C)C
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Synonyms
PROTAC Linker 22
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (624.18 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.2418 mL | 31.2090 mL | 62.4181 mL | 156.0452 mL |
| 5 mM | 1.2484 mL | 6.2418 mL | 12.4836 mL | 31.2090 mL | |
| 10 mM | 0.6242 mL | 3.1209 mL | 6.2418 mL | 15.6045 mL | |
| 15 mM | 0.4161 mL | 2.0806 mL | 4.1612 mL | 10.4030 mL | |
| 20 mM | 0.3121 mL | 1.5605 mL | 3.1209 mL | 7.8023 mL | |
| 25 mM | 0.2497 mL | 1.2484 mL | 2.4967 mL | 6.2418 mL | |
| 30 mM | 0.2081 mL | 1.0403 mL | 2.0806 mL | 5.2015 mL | |
| 40 mM | 0.1560 mL | 0.7802 mL | 1.5605 mL | 3.9011 mL | |
| 50 mM | 0.1248 mL | 0.6242 mL | 1.2484 mL | 3.1209 mL | |
| 60 mM | 0.1040 mL | 0.5202 mL | 1.0403 mL | 2.6008 mL | |
| 80 mM | 0.0780 mL | 0.3901 mL | 0.7802 mL | 1.9506 mL | |
| 100 mM | 0.0624 mL | 0.3121 mL | 0.6242 mL | 1.5605 mL |
NH2-C2-NH-Boc Related Classifications
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