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Cat. No.: HY-N20647

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Jioglutolide

Jioglutolide is a cyclopentane monoterpene and weak testosterone 5α-reductase inhibitor. Jioglutolide is isolated from steamed roots of Rehmannia glutinosa var. hueichingensis. Jioglutolide is applicable to research on allergies, anemia, diabetes, and menopause-related conditions.

For research use only. We do not sell to patients.

CAS No.: 124902-18-7
Formula: C₉H₁₄O₄
Molecular Weight:186.21

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Jioglutolide Chemical Structure

CAS No.: 124902-18-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

Jioglutolide binds stably to human AKT1 protein with an average binding energy of -5.81 kcal/mol^[1].
Jioglutolide binds stably to human PTGS2 protein with an average binding energy of -5.95 kcal/mol^[1].
Jioglutolide shows weak inhibition of testosterone 5α-reductase^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 124902-18-7
Molecular Weight 186.21
Formula C₉H₁₄O₄
SMILES

O[C@H]1[C@@]2([H])[C@@](COC(C2)=O)([H])[C@@](O)(C1)C
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Park J, et al. Exploring the Therapeutic Potential of Rehmannia glutinosa: A Network Pharmacology and Molecular Docking Analysis Across Multiple Diseases. Curr Issues Mol Biol. 2025 May 3;47(5):329. [Content Brief]

[2]. Morota T, et al. Five cyclopentanoid monoterpenes from Rehmannia glutinosa[J]. Phytochemistry, 1989, 28(9): 2385-2391.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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