JNJ-26993135
Based on 1 Customer Validation
JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM.
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 841202-16-2
- Formula: C20H20N2O3S
- Molecular Weight:368.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 33r
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Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane
Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane
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[PMID: 18588282] |
Chemical Information
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CAS No. 841202-16-2
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Appearance Solid
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Molecular Weight 368.45
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Formula C20H20N2O3S
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Color Off-white to light yellow
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SMILES
O=C(C1CCN(CC2=CC=C(OC3=NC4=CC=CC=C4S3)C=C2)CC1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 12.5 mg/mL (33.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7141 mL | 13.5704 mL | 27.1407 mL | 67.8518 mL |
| 5 mM | 0.5428 mL | 2.7141 mL | 5.4281 mL | 13.5704 mL | |
| 10 mM | 0.2714 mL | 1.3570 mL | 2.7141 mL | 6.7852 mL | |
| 15 mM | 0.1809 mL | 0.9047 mL | 1.8094 mL | 4.5235 mL | |
| 20 mM | 0.1357 mL | 0.6785 mL | 1.3570 mL | 3.3926 mL | |
| 25 mM | 0.1086 mL | 0.5428 mL | 1.0856 mL | 2.7141 mL | |
| 30 mM | 0.0905 mL | 0.4523 mL | 0.9047 mL | 2.2617 mL |
JNJ-26993135 Related Classifications
HY-119023 Related Classifications
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