JNJ-26993135
Based on 1 Customer Validation
JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.30%
- CAS No.: 841202-16-2
- Formule: C20H20N2O3S
- Masse moléculaire:368.45
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 33r
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Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane
Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane
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[PMID: 18588282] |
Chemical Information
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CAS No. 841202-16-2
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Appearance Solid
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Masse moléculaire 368.45
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Formule C20H20N2O3S
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Color Off-white to light yellow
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SMILES
O=C(C1CCN(CC2=CC=C(OC3=NC4=CC=CC=C4S3)C=C2)CC1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 12.5 mg/mL (33.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7141 mL | 13.5704 mL | 27.1407 mL | 67.8518 mL |
| 5 mM | 0.5428 mL | 2.7141 mL | 5.4281 mL | 13.5704 mL | |
| 10 mM | 0.2714 mL | 1.3570 mL | 2.7141 mL | 6.7852 mL | |
| 15 mM | 0.1809 mL | 0.9047 mL | 1.8094 mL | 4.5235 mL | |
| 20 mM | 0.1357 mL | 0.6785 mL | 1.3570 mL | 3.3926 mL | |
| 25 mM | 0.1086 mL | 0.5428 mL | 1.0856 mL | 2.7141 mL | |
| 30 mM | 0.0905 mL | 0.4523 mL | 0.9047 mL | 2.2617 mL |
JNJ-26993135 Related Classifications
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