JNK-1-IN-1
JNK-1-IN-1 is a JNK-1 inhibitor. JNK-1-IN-1 also inhibits MKK7 with an IC50 of 7.8μM. JNK-1-IN-1 bind to MKK7cp and acts as an inhibitor of JNK-1.
For research use only. We do not sell to patients.
- CAS No.: 1262406-02-9
- Formula: C24H22N6S
- Molecular Weight:426.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
JNK1 |
JNK-1-IN-1 (Compound 2) has affinity for binding to Jnk1-u, p38α-u, ERK2-u in HepG2 human hepatoma cells with Kd values of 11, 18, 18, respectively[1].
JNK-1-IN-1 inhibits MKK7cp in HepG2 human hepatoma cells with IC50 values of 7.8.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1262406-02-9
-
Molecular Weight 426.54
-
Formula C24H22N6S
-
SMILES
CCCN(C1=NC(C=CC=C2)=C2S1)CC(C=C3)=CC=C3C4=CC=CC=C4C5=NNN=N5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)