JNK-1-IN-1
JNK-1-IN-1 is a JNK-1 inhibitor. JNK-1-IN-1 also inhibits MKK7 with an IC50 of 7.8μM. JNK-1-IN-1 bind to MKK7cp and acts as an inhibitor of JNK-1.
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- CAS No.: 1262406-02-9
- Formule: C24H22N6S
- Masse moléculaire:426.54
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
JNK1 |
In Vitro
JNK-1-IN-1 (Compound 2) has affinity for binding to Jnk1-u, p38α-u, ERK2-u in HepG2 human hepatoma cells with Kd values of 11, 18, 18, respectively[1].
JNK-1-IN-1 inhibits MKK7cp in HepG2 human hepatoma cells with IC50 values of 7.8.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 1262406-02-9
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Masse moléculaire 426.54
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Formule C24H22N6S
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SMILES
CCCN(C1=NC(C=CC=C2)=C2S1)CC(C=C3)=CC=C3C4=CC=CC=C4C5=NNN=N5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)