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Cat. No.: HY-Y0075

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2-Naphthaldehyde

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2-Naphthaldehyde is a naphthalene-based bi-aromatic aldehyde compound. 2-Naphthaldehyde scavenges DPPH and ABTS⁺ free radicals, and exerts reductive effects by donating hydrogen atoms to terminate free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD⁺-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized to 2-naphthoic acid. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases.

For research use only. We do not sell to patients.

Purity: 99.80%
CAS No.: 66-99-9
Formula: C₁₁H₈O
Molecular Weight:156.18

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

2-Naphthaldehyde Chemical Structure

CAS No.: 66-99-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

2-Naphthaldehyde (20 μM; varied concentrations) is efficiently oxidized by purified SALDH from Pseudomonas sp. strain C6, with an apparent K_m of 3.5 μM, moderate substrate inhibition (K_i of 136 μM), and activity equal to ~44% of its activity with salicylaldehyde^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 66-99-9
Appearance Solid
Molecular Weight 156.18
Formula C₁₁H₈O
Color Off-white to yellow
SMILES

O=CC1=CC2=C(C=CC=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (320.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

6.4029 mL

32.0143 mL

64.0287 mL

5 mM

1.2806 mL

6.4029 mL

12.8057 mL

10 mM

0.6403 mL

3.2014 mL

6.4029 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Matsushita Y, et al. Antioxidant and cytotoxic activities of naphthalene derivatives from Diospyros kaki. Journal of Wood Science, 2011, 57: 161-165.

[2]. Singh R, et al. Purification and characterization of NAD+ -dependent salicylaldehyde dehydrogenase from carbaryl-degrading Pseudomonas sp. strain C6. Applied biochemistry and biotechnology. 2014 Jan;172(2):806-19.

[3]. Oladipo SD, et al. Antidiabetes and antioxidant potential of Schiff bases derived from 2-naphthaldehye and substituted aromatic amines: Synthesis, crystal structure, Hirshfeld surface analysis, computational, and studies. Heliyon. 2024 Jan 15;10(1):e23174.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	6.4029 mL	32.0143 mL	64.0287 mL	160.0717 mL
	5 mM	1.2806 mL	6.4029 mL	12.8057 mL	32.0143 mL
	10 mM	0.6403 mL	3.2014 mL	6.4029 mL	16.0072 mL
	15 mM	0.4269 mL	2.1343 mL	4.2686 mL	10.6714 mL
	20 mM	0.3201 mL	1.6007 mL	3.2014 mL	8.0036 mL
	25 mM	0.2561 mL	1.2806 mL	2.5611 mL	6.4029 mL
	30 mM	0.2134 mL	1.0671 mL	2.1343 mL	5.3357 mL
	40 mM	0.1601 mL	0.8004 mL	1.6007 mL	4.0018 mL
	50 mM	0.1281 mL	0.6403 mL	1.2806 mL	3.2014 mL
	60 mM	0.1067 mL	0.5336 mL	1.0671 mL	2.6679 mL
	80 mM	0.0800 mL	0.4002 mL	0.8004 mL	2.0009 mL
	100 mM	0.0640 mL	0.3201 mL	0.6403 mL	1.6007 mL

Keywords

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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2-Naphthaldehyde

Covalent Screening Library

Traditional Chinese Medicine Active Compound Library

Human Metabolite Library

Cysteine Targeted Covalent Library

Cysteine Targeted Covalent Fragment Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Covalent Screening Library Plus

Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Drug Fragment Library

Covalent Fragment Library

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

2-Naphthaldehyde

Covalent Screening Library

Traditional Chinese Medicine Active Compound Library

Human Metabolite Library

Cysteine Targeted Covalent Library

Cysteine Targeted Covalent Fragment Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Covalent Screening Library Plus

Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Drug Fragment Library

Covalent Fragment Library

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

2-Naphthaldehyde Related Classifications

HY-Y0075 Related Classifications