DL-α-Tocotrienol
Alpha-Tocotrienol is a vitamin E analog with anti-apoptotic neuroprotective action and antioxidant properties. Alpha-Tocotrienol prevents oxidative stress-independent apoptotic cell death, DNA cleavage, and nuclear morphological changes.
For research use only. We do not sell to patients.
- CAS No.: 1721-51-3
- Formula: C29H44O2
- Molecular Weight:424.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
110 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
|
[PMID: 1433170] |
| HepG2 | IC50 |
380 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
|
[PMID: 1433170] |
| HepG2 | IC50 |
94 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
|
[PMID: 1433170] |
Chemical Information
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CAS No. 1721-51-3
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Molecular Weight 424.66
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Formula C29H44O2
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SMILES
OC1=C(C)C(C)=C2C(CCC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(C)O2)=C1C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)