Aspalathin
Aspalathin is a C-glycosyldihydrochalcone flavonoid and antioxidant.Aspalathin functions as an antimutagen.Aspalathin can be absorbed by pig intestine as a C-glycoside, and can also be cleaved into its aglycone and sugar moiety.Aspalathin is found in Aspalathus linearis (rooibos).
For research use only. We do not sell to patients.
- CAS No.: 6027-43-6
- Formula: C21H24O11
- Molecular Weight:452.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Aspalathin (5 μg/mL) with optimized β-D-glucuronidase treatment (2096 U/mL for urine; 4611.2 U/mL for plasma) and SPE cleanup procedures achieves measurable recovery of aspalathin from spiked blank urine and plasma samples, with plasma showing higher recovery and variable precision depending on enzymatic treatment. Incubation times were 3 h for urine and 1 h for plasma enzymatic treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Pig (6 months old, 94-99 kg)[1]
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Dosage:157 mg/kg ; 167 mg/kg
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Administration:p.o.; daily; 11 days
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Result:Identified six substances derived from aspalathin in urine: parent aspalathin, methylated aspalathin, glucuronidated aspalathin, glucuronidated and methylated aspalathin, a glucuronidated aglycone of aspalathin, and a methylated eriodictyol metabolite with two glucuronic acid moieties.
Detected methylated aspalathin as the major metabolite in enzymatically treated urine samples.
Chemical Information
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CAS No. 6027-43-6
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Molecular Weight 452.41
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Formula C21H24O11
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SMILES
O[C@H]1[C@H](C2=C(C(C(CCC3=CC(O)=C(C=C3)O)=O)=C(C=C2O)O)O)O[C@@H]([C@H]([C@@H]1O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aspalathin Related Classifications
HY-N11738 Related Classifications
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