CW2158
CW2158 (Compound 13) is a modulator for exportin1 (XPO1) ,which disrupts the chromatin binding, inhibits NFAT transcription factors and activation of T cells.
For research use only. We do not sell to patients.
- Formula: C14H8F4N4O2
- Molecular Weight:340.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CW2158 (10 nM-10 μM) inhibits the expression of IL-2 (6 h) and viability (24 h) of Jurkat cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jurkat
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Concentration:10 nM-10 μM
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Incubation Time:24 h
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Result:Inhibited cell viability of Jurkats.
Chemical Information
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Molecular Weight 340.23
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Formula C14H8F4N4O2
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SMILES
FC(F)(F)C(N=C1NN2C(C=C(C)C2=O)=O)=NC3=C1C(F)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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