1,8-Octanedithiol
Based on 1 Customer Validation
1,8-Octanedithiol is a PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.00%
- CAS 番号: 1191-62-4
- 分子式: C8H18S2
- 分子量:178.35
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保管条件:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E94 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1191-62-4
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性状 Liquid
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分子量 178.35
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分子式 C8H18S2
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Color Colorless to light yellow
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SMILES
SCCCCCCCCS
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (560.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (239 KB)
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SDS (393 KB)
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- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6070 mL | 28.0348 mL | 56.0695 mL | 140.1738 mL |
| 5 mM | 1.1214 mL | 5.6070 mL | 11.2139 mL | 28.0348 mL | |
| 10 mM | 0.5607 mL | 2.8035 mL | 5.6070 mL | 14.0174 mL | |
| 15 mM | 0.3738 mL | 1.8690 mL | 3.7380 mL | 9.3449 mL | |
| 20 mM | 0.2803 mL | 1.4017 mL | 2.8035 mL | 7.0087 mL | |
| 25 mM | 0.2243 mL | 1.1214 mL | 2.2428 mL | 5.6070 mL | |
| 30 mM | 0.1869 mL | 0.9345 mL | 1.8690 mL | 4.6725 mL | |
| 40 mM | 0.1402 mL | 0.7009 mL | 1.4017 mL | 3.5043 mL | |
| 50 mM | 0.1121 mL | 0.5607 mL | 1.1214 mL | 2.8035 mL | |
| 60 mM | 0.0934 mL | 0.4672 mL | 0.9345 mL | 2.3362 mL | |
| 80 mM | 0.0701 mL | 0.3504 mL | 0.7009 mL | 1.7522 mL | |
| 100 mM | 0.0561 mL | 0.2803 mL | 0.5607 mL | 1.4017 mL |