11-Hydroxytephrosin
Based on 1 Customer Validation
11-Hydroxytephrosin is a potent NF-κB inhibitor with an IC50 of 0.19 μM or 4.21 μM. 11-Hydroxytephrosin is isolated from A. fruticosa. 11-Hydroxytephrosin inhibits the activation of NF-κB. 11-Hydroxytephrosin can be used in research related to cervical cancer and inflammatory diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 72458-85-6
- 分子式: C23H22O8
- 分子量:426.42
-
保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.19 μM
Compound: 2
|
Inhibition of TNF-alpha-induced NF-kappaB activation in human HeLa cells by SEAP reporter gene assay
Inhibition of TNF-alpha-induced NF-kappaB activation in human HeLa cells by SEAP reporter gene assay
|
[PMID: 18841906] |
| RAW264.7 | IC50 |
4.21 μM
Compound: 2
|
Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells by SEAP reporter gene assay
Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells by SEAP reporter gene assay
|
[PMID: 18841906] |
11-Hydroxytephrosin (24 h) potently inhibits TNF-α-induced NF-κB activation in HeLa cells with an IC50 of 0.19 μM, and shows no significant cytotoxicity at concentrations up to 30 μM[1].
11-Hydroxytephrosin (24 h) inhibits LPS-induced NF-κB activation in RAW264.7 cells with an IC50 of 4.21 μM, and shows no significant cytotoxicity at concentrations up to 30 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 72458-85-6
-
性状 Solid
-
分子量 426.42
-
分子式 C23H22O8
-
Color White to off-white
-
SMILES
O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC(O)=C14
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
-
データシート (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
11-Hydroxytephrosin 関連分類
HY-N1022 関連分類
Powered by Bioz