3-Phenylphenol
Based on 1 Customer Validation
3-Phenylphenol is a secondary metabolite. 3-Phenylphenol can induce the hbp gene cluster in Pseudomonas sp. strain P1B16. 3-Phenylphenol can bind to the Sge1 transcription factor of Fusarium oxysporum f. sp. cubense and disrupt the function of virulence regulators. 3-Phenylphenol can be used in studies related to banana fusarium wilt.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.86%
- CAS 番号: 580-51-8
- 分子式: C12H10O
- 分子量:170.21
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保管条件:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
25 μg/mL
Compound: 7
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Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
| HT-29 | IC50 |
28 μg/mL
Compound: 7
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Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
| MCF7 | IC50 |
27.4 μg/mL
Compound: 7
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Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
3-Phenylphenol (0.1-100 mM; 72 h) induces the hbp operon in the Pseudomonas sp. P1B16/egfp biosensor strain[1].
3-Phenylphenol exhibits strong binding affinity to the Sge1 protein of Fusarium oxysporum f. sp. cubense, with a binding energy of -6.7 kcal/mol[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 580-51-8
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性状 Solid
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分子量 170.21
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分子式 C12H10O
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Color Off-white to light yellow
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SMILES
OC1=CC=CC(=C1)C=2C=CC=CC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Suman J, et al. Transformation of hydroxylated polychlorinated biphenyls by bacterial 2-hydroxybiphenyl 3-monooxygenase. Chemosphere. 2024;349:140909. [Content Brief]
[2]. Sonkar P, et al. In silico profiling, docking analysis, and protein interactions of secondary metabolites in Musa spp. Against the SGE1 protein of Fusarium oxysporum f. sp. cubense. Comput Biol Chem. 2024;113:108230. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
3-Phenylphenol 関連分類
HY-W016983 関連分類
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