6-Hydroxyisatin
Based on 1 Customer Validation
6-Hydroxyisatin is an atrial natriuretic peptide receptor (ANP receptor) inhibitor. 6-Hydroxyisatin exhibits inhibitory activity against ANP-stimulated particulate guanylyl cyclase activity in rat brain cell membranes.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95.86%
- CAS 番号: 116569-08-5
- 分子式: C8H5NO3
- 分子量:163.13
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat brain membranes by 54.4%[2].
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat heart membranes by 16.7%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 116569-08-5
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性状 Solid
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分子量 163.13
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分子式 C8H5NO3
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Color Orange to red
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SMILES
O=C1NC2=C(C=CC(O)=C2)C1=O
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Structure Classification
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Initial Source
Micromonospora carbonacea
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 2 mg/mL (12.26 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1301 mL | 30.6504 mL | 61.3008 mL | 153.2520 mL |
| 5 mM | 1.2260 mL | 6.1301 mL | 12.2602 mL | 30.6504 mL | |
| 10 mM | 0.6130 mL | 3.0650 mL | 6.1301 mL | 15.3252 mL |
6-Hydroxyisatin 関連分類
HY-W092067 関連分類
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Keywords
- 6-Hydroxyisatin
- 116569-08-5
- Natriuretic Peptide Receptor (NPR)
- DFT
- rat brain membranes
- atrial natriuretic peptide receptors
- keto/phenol tautomerism
- atrial natriuretic peptide
- rat heart membranes
- Sandmeyer’s procedure
- UV/Vis absorption
- Streptomyces sp. strain B1848
- particulate guanylyl cyclase
- Inhibitor
- inhibitor
- inhibit