Calcitriol-d6
Based on 1 Customer Validation
Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.27%
- CAS 番号: 78782-99-7
- 分子式: C27H38D6O3
- 分子量:422.67
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保管条件:Powder -20°C, 3 years , 4°C, 2 years
* The compound is unstable in solutions, freshly prepared is recommended.
生物活性
Calcitriol-d6 can be used as an internal standard for the quantitative analysis of Calcitriol (HY-10002) in plasma[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 78782-99-7
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非標識Cas 32222-06-3
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性状 Solid
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分子量 422.67
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分子式 C27H38D6O3
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Color White to off-white
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SMILES
C=C1/C(C[C@H](C[C@@H]1O)O)=C\C=C2CCC[C@]3(C)[C@@H]([C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)CC[C@@]/23[H]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years * The compound is unstable in solutions, freshly prepared is recommended.
溶剤 & 溶解度
DMSO : 50 mg/mL (118.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Nair SN, et al. A liquid chromatography/electrospray ionization tandem mass spectrometric method for quantification of asiatic acid from plasma: application to pharmacokinetic study in rats. Rapid Commun Mass Spectrom. 2012 Sep 15;26(17):1899-908. [Content Brief]
[2]. Canalejo, et al. The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3659 mL | 11.8296 mL | 23.6591 mL | 59.1478 mL |
| 5 mM | 0.4732 mL | 2.3659 mL | 4.7318 mL | 11.8296 mL | |
| 10 mM | 0.2366 mL | 1.1830 mL | 2.3659 mL | 5.9148 mL | |
| 15 mM | 0.1577 mL | 0.7886 mL | 1.5773 mL | 3.9432 mL | |
| 20 mM | 0.1183 mL | 0.5915 mL | 1.1830 mL | 2.9574 mL | |
| 25 mM | 0.0946 mL | 0.4732 mL | 0.9464 mL | 2.3659 mL | |
| 30 mM | 0.0789 mL | 0.3943 mL | 0.7886 mL | 1.9716 mL | |
| 40 mM | 0.0591 mL | 0.2957 mL | 0.5915 mL | 1.4787 mL | |
| 50 mM | 0.0473 mL | 0.2366 mL | 0.4732 mL | 1.1830 mL | |
| 60 mM | 0.0394 mL | 0.1972 mL | 0.3943 mL | 0.9858 mL | |
| 80 mM | 0.0296 mL | 0.1479 mL | 0.2957 mL | 0.7393 mL | |
| 100 mM | 0.0237 mL | 0.1183 mL | 0.2366 mL | 0.5915 mL |