Miriplatin
Based on 3 publication(s) in Google Scholar
Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 141977-79-9
- 分子式: C34H68N2O4Pt
- 分子量:764.00
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 Miriplatin
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生物活性
製品説明
体外実験
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 141977-79-9
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性状 Solid
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分子量 764.00
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分子式 C34H68N2O4Pt
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Color White to off-white
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SMILES
NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.[Pt+2]
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別名
SM-11355
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (3)
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Journal Impact Factor
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Most Recent
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J Control Release
Nanoparticle-delivered miriplatin ultrasmall dots suppress triple negative breast cancer lung metastasis by targeting circulating tumor cells. [Abstract]2021 Jan 10:329:833-846. PMID: 33045314 -
J Mol Med (Berl)
2019 Aug;97(8):1183-1193. PMID: 31201471 -
溶剤 & 溶解度
体外:
chloroform : 43.33 mg/mL (56.71 mM; Need ultrasonic; DMSO can inactivate Miriplatin's activity)
Acetone : < 1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
DMF : < 1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
H2O : < 0.1 mg/mL (insoluble; DMSO can inactivate Miriplatin's activity)
* Miriplatin is usually formulated as a suspension.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. [Content Brief]
[2]. Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| chloroform | 1 mM | 1.3089 mL | 6.5445 mL | 13.0890 mL | 32.7225 mL |
| 5 mM | 0.2618 mL | 1.3089 mL | 2.6178 mL | 6.5445 mL | |
| 10 mM | 0.1309 mL | 0.6545 mL | 1.3089 mL | 3.2723 mL | |
| 15 mM | 0.0873 mL | 0.4363 mL | 0.8726 mL | 2.1815 mL | |
| 20 mM | 0.0654 mL | 0.3272 mL | 0.6545 mL | 1.6361 mL | |
| 25 mM | 0.0524 mL | 0.2618 mL | 0.5236 mL | 1.3089 mL | |
| 30 mM | 0.0436 mL | 0.2182 mL | 0.4363 mL | 1.0908 mL | |
| 40 mM | 0.0327 mL | 0.1636 mL | 0.3272 mL | 0.8181 mL | |
| 50 mM | 0.0262 mL | 0.1309 mL | 0.2618 mL | 0.6545 mL |
Miriplatin 関連分類
HY-16325A 関連分類
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