Boc-C1-PEG2-C4-Cl
Based on 1 Customer Validation
Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.81%
- CAS 番号: 1835705-53-7
- 分子式: C14H27ClO4
- 分子量:294.81
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTAC technology employs small molecules that recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases is reported. Boc-C1-PEG2-C4-Cl is designated as 6-2-2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1835705-53-7
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性状 Liquid (Density: 1.026±0.06 g/cm3)
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分子量 294.81
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分子式 C14H27ClO4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)COCCOCCCCCCCl
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別名
PROTAC Linker 1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 50 mg/mL (169.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3920 mL | 16.9601 mL | 33.9202 mL | 84.8004 mL |
| 5 mM | 0.6784 mL | 3.3920 mL | 6.7840 mL | 16.9601 mL | |
| 10 mM | 0.3392 mL | 1.6960 mL | 3.3920 mL | 8.4800 mL | |
| 15 mM | 0.2261 mL | 1.1307 mL | 2.2613 mL | 5.6534 mL | |
| 20 mM | 0.1696 mL | 0.8480 mL | 1.6960 mL | 4.2400 mL | |
| 25 mM | 0.1357 mL | 0.6784 mL | 1.3568 mL | 3.3920 mL | |
| 30 mM | 0.1131 mL | 0.5653 mL | 1.1307 mL | 2.8267 mL | |
| 40 mM | 0.0848 mL | 0.4240 mL | 0.8480 mL | 2.1200 mL | |
| 50 mM | 0.0678 mL | 0.3392 mL | 0.6784 mL | 1.6960 mL | |
| 60 mM | 0.0565 mL | 0.2827 mL | 0.5653 mL | 1.4133 mL | |
| 80 mM | 0.0424 mL | 0.2120 mL | 0.4240 mL | 1.0600 mL | |
| 100 mM | 0.0339 mL | 0.1696 mL | 0.3392 mL | 0.8480 mL |
Boc-C1-PEG2-C4-Cl 関連分類
HY-108371 関連分類
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