Cl-C6-PEG4-O-CH2COOH
Based on 1 Customer Validation
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1799506-30-1
- 分子式: C16H31ClO7
- 分子量:370.87
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1799506-30-1
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性状 Oil
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分子量 370.87
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分子式 C16H31ClO7
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Color Colorless to light yellow
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SMILES
ClCCCCCCOCCOCCOCCOCCOCC(O)=O
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別名
PROTAC Linker 4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
Ethanol : 100 mg/mL (269.64 mM; Need ultrasonic)
DMSO : 100 mg/mL (269.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.6964 mL | 13.4818 mL | 26.9636 mL | 67.4091 mL |
| 5 mM | 0.5393 mL | 2.6964 mL | 5.3927 mL | 13.4818 mL | |
| 10 mM | 0.2696 mL | 1.3482 mL | 2.6964 mL | 6.7409 mL | |
| 15 mM | 0.1798 mL | 0.8988 mL | 1.7976 mL | 4.4939 mL | |
| 20 mM | 0.1348 mL | 0.6741 mL | 1.3482 mL | 3.3705 mL | |
| 25 mM | 0.1079 mL | 0.5393 mL | 1.0785 mL | 2.6964 mL | |
| 30 mM | 0.0899 mL | 0.4494 mL | 0.8988 mL | 2.2470 mL | |
| 40 mM | 0.0674 mL | 0.3370 mL | 0.6741 mL | 1.6852 mL | |
| 50 mM | 0.0539 mL | 0.2696 mL | 0.5393 mL | 1.3482 mL | |
| 60 mM | 0.0449 mL | 0.2247 mL | 0.4494 mL | 1.1235 mL | |
| 80 mM | 0.0337 mL | 0.1685 mL | 0.3370 mL | 0.8426 mL | |
| 100 mM | 0.0270 mL | 0.1348 mL | 0.2696 mL | 0.6741 mL |