Hapten
Hapten, also known as incomplete antigen, refers to simple small molecule antigen that only has immune response specificity but no immunogenicity, such as certain polysaccharides, lipids, and drugs. Haptens are small molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself. Attaching of haptens to a carrier molecule lead to a complete antigen. Haptens have been used to study allergic contact dermatitis (ACD) and the mechanisms of inflammatory bowel disease (IBD) to induce autoimmune-like responses.
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Hapten 関連製品 (28)
関連製品 (28)
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Monobenzone
(Monobenzone)
0 ImagesMonobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and exhibits good potential for vitiligo research. Monobenzone is a potent inhibitor of RNR (Ribonucleotide reductase) enzyme activity by targeting RRM2 (a regulatory small subunit M2 of RNR) protein, and thus has significant anti-leukemia efficacy in vitro and in vivo. Monobenzone inhibits acute myeloid leukemia (AML) cells proliferation and DNA synthesis, induces cell cycle arrest, and Apoptosis .
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J10-1
0 ImagesJ10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation.
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di-DTPA-LTL
0 Images製品番号: HY-155446di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients.
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di-DTPA TL
0 Images製品番号: HY-155445CAS 番号: 136687-39-3di-DTPA TL is a hydrophilic bivalent DTPA hapten that can be used for tumor research.
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IMP 241
0 Images製品番号: HY-155469CAS 番号: 391267-27-9IMP 241 is a di-HSG bivalent hapten.
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TETS-Methyl benzoate
0 Images製品番号: HY-161005CAS 番号: 2107375-54-0TETS-Methyl benzoate(compound 2j) is a haptendirectly conjugated to the carrier protein via carboxylic acid function using the standard activated ester method.
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Dicamba-(CH2)5-acid
0 Images製品番号: HY-155455CAS 番号: 2892008-07-8Hapten Dca is an immunizing hapten. Hapten Dca is activated by a solution of N, N′-disuccinimidyl carbonate. Hapten Dca with a carboxyl functional group is conjugated to proteins.
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Ursodeoxycholic acid 7-N-acetylglucosaminide
0 Images製品番号: HY-149754CAS 番号: 145624-10-8Ursodeoxycholic acid 7-N-acetylglucosaminide is an immunizing and heterologous hapten.
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Dicamba 1-azidopropane
0 Images製品番号: HY-163014CAS 番号: 2892008-32-9Dicamba 1-azidopropane (DCn) is an immunizing and heterologous hapten. Dicamba 1-azidopropane can be used to generate monoclonal antibodies specific of Dicamba.
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AG3.0
0 Images製品番号: HY-155447CAS 番号: 136687-43-9AG3.0 is a symmetric di-HSG bivalent hapten. AG3.0 can be used for the research of pretargeted radioimmunotherapy.
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Photolumazine I
0 Images製品番号: HY-157282CAS 番号: 29161-67-9別名: PLIPhotolumazine I(PLI) is a vitamin B-based hapten.Photolumazine Icanactivates Mucosal-associated Invariant T clones.
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Methylthiomcresol-succinaldehydic acid
0 Images製品番号: HY-149753CAS 番号: 848486-57-7Methylthiomcresol-succinaldehydic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
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(±)-Bupropion-(CH2)3-OH hydrochloride
0 Images製品番号: HY-155495CAS 番号: 80762-38-5(±)-Bupropion-(CH2)3-OH hydrochloride (compound 3) is a hapten useful in the radioimmunoassay of Bupropion (HY-B0403).
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Methyl isonicotinate-(CH2)2-COOH
0 Images製品番号: HY-157262CAS 番号: 2710224-09-0Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity.
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Dicamba-5-hydroxypentanoic acid
0 Images製品番号: HY-163013CAS 番号: 2892008-29-4Dicamba-5-hydroxypentanoic acid (DCo), synthesized from commercially available 5-hydroxy-dicamba, is an immunizing and heterologous hapten. Dicamba-5-hydroxypentanoic acid (DCo) is chemoselectively activated using one equivalent of DSC (N,N- disuccinimidyl carbonate).
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Atrazine-acetic acid
0 Images製品番号: HY-163023CAS 番号: 193889-80-4Atrazine-acetic acid is an immunizing and heterologous hapten.
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Methylthiomcresol-C1-benzoic acid
0 Images製品番号: HY-149752CAS 番号: 848486-56-6Methylthiomcresol-C1-benzoic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
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