(+)-Asarinin
(+)-Asarinin (Isosesamin) is a lignan that can be found in Acronychia mulleri. (+)-Asarinin exhibits antitubercular and antimycobacterial activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 133-03-9
- 分子式: C20H18O6
- 分子量:354.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
>60 μM
Compound: 5
|
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay
|
[PMID: 22381047] |
| HepG2 | IC50 |
7.1 μM
Compound: 5
|
Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis
Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis
|
[PMID: 22381047] |
| NIH3T3 | IC50 |
0.2 μM
Compound: 1
|
Cytotoxicity against murine 3T3 cells by MTT assay
Cytotoxicity against murine 3T3 cells by MTT assay
|
[PMID: 17253847] |
体外実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 133-03-9
-
分子量 354.35
-
分子式 C20H18O6
-
SMILES
[H][C@]1(CO[C@@H]2C3=CC=C4OCOC4=C3)[C@]2([H])CO[C@H]1C5=CC=C6OCOC6=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)