Alpha-tocopheryloxyacetic acid
Alpha-tocopheryloxyacetic acid (alpha-TEA) is an inducer of cancer cell apoptosis pathway. Alpha-tocopheryloxyacetic acid is promising for research of solid and hematological malignancies.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 261929-52-6
- 分子式: C31H52O4
- 分子量:488.74
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | EC50 |
51 μM
Compound: alpha-TEA
|
Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis
Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis
|
[PMID: 23092906] |
| MDA-MB-231 | EC50 |
35 μM
Compound: alpha-TEA
|
Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis
Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis
|
[PMID: 23092906] |
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 261929-52-6
-
分子量 488.74
-
分子式 C31H52O4
-
SMILES
O=C(O)COC1=C(C)C(C)=C2C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C1C
-
別名
alpha-TEA
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)