DL-α-Tocotrienol
Alpha-Tocotrienol is a vitamin E analog with anti-apoptotic neuroprotective action and antioxidant properties. Alpha-Tocotrienol prevents oxidative stress-independent apoptotic cell death, DNA cleavage, and nuclear morphological changes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1721-51-3
- 分子式: C29H44O2
- 分子量:424.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
110 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
|
[PMID: 1433170] |
| HepG2 | IC50 |
380 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
|
[PMID: 1433170] |
| HepG2 | IC50 |
94 μM
Compound: d,l-alpha-tocotrienol
|
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
|
[PMID: 1433170] |
化学情報
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CAS 番号 1721-51-3
-
分子量 424.66
-
分子式 C29H44O2
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SMILES
OC1=C(C)C(C)=C2C(CCC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(C)O2)=C1C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)