AMCA
Based on 1 Customer Validation
AMCA (4-(Aminomethyl)-1-cyclohexanecarboxylic acid) is a PROTAC linker. AMCA can be used to synthesize the PROTAC molecule YB-3–17 (HY-170405).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.58%
- CAS 番号: 701-54-2
- 分子式: C8H15NO2
- 分子量:157.21
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
More
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | IC50 |
>2.0 × 105M
Compound: COVC-3899353050
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
10.6019/CHEMBL4651402 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 701-54-2
-
性状 Solid
-
分子量 157.21
-
分子式 C8H15NO2
-
Color White to light brown
-
SMILES
O=C(C1CCC(CN)CC1)O
-
別名
4-(Aminomethyl)-1-cyclohexanecarboxylic acid
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 87.5 mg/mL (556.58 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (265 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.3609 mL | 31.8046 mL | 63.6092 mL | 159.0230 mL |
| 5 mM | 1.2722 mL | 6.3609 mL | 12.7218 mL | 31.8046 mL | |
| 10 mM | 0.6361 mL | 3.1805 mL | 6.3609 mL | 15.9023 mL | |
| 15 mM | 0.4241 mL | 2.1203 mL | 4.2406 mL | 10.6015 mL | |
| 20 mM | 0.3180 mL | 1.5902 mL | 3.1805 mL | 7.9511 mL | |
| 25 mM | 0.2544 mL | 1.2722 mL | 2.5444 mL | 6.3609 mL | |
| 30 mM | 0.2120 mL | 1.0602 mL | 2.1203 mL | 5.3008 mL | |
| 40 mM | 0.1590 mL | 0.7951 mL | 1.5902 mL | 3.9756 mL | |
| 50 mM | 0.1272 mL | 0.6361 mL | 1.2722 mL | 3.1805 mL | |
| 60 mM | 0.1060 mL | 0.5301 mL | 1.0602 mL | 2.6504 mL | |
| 80 mM | 0.0795 mL | 0.3976 mL | 0.7951 mL | 1.9878 mL | |
| 100 mM | 0.0636 mL | 0.3180 mL | 0.6361 mL | 1.5902 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
AMCA 関連分類
HY-A0102 関連分類
Powered by Bioz