Andrographiside
Based on 1 Customer Validation
Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP). Andrographiside is a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96%
- CAS 番号: 82209-76-5
- 分子式: C26H40O10
- 分子量:512.59
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | GI50 |
28.83 μM
Compound: 13
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Antiproliferative activity against human HL60 cells by trypan blue assay
Antiproliferative activity against human HL60 cells by trypan blue assay
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[PMID: 18357994] |
化学情報
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CAS 番号 82209-76-5
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性状 Solid
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分子量 512.59
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分子式 C26H40O10
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Color White to off-white
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SMILES
C[C@]12[C@@](CCC([C@H]2C/C=C3[C@@H](COC\3=O)O)=C)([H])[C@@](C)([C@@H](CC1)O)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Kapil A, et al. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol. 1993 Jul 6;46(1):182-5. [Content Brief]
[2]. Tandi A, Roy DN. Andrographiside acts as a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins (LasR and RhlI), Pseudomonas quinolone signal regulator (PqsR) and Pellicle B of PEL Operon: An in silico and in vitro approach. Comput Biol Chem. 2026;122:108894. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)