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製品番号: HY-146467

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Anticancer agent 62

Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC₅₀ values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition.

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CAS 番号: 2413148-58-8
分子式: C₂₀H₁₈N₃Na₂O₈PS
分子量:537.39

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Anticancer agent 62 構造式

CAS 番号: 2413148-58-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
Bel-7402	IC₅₀	0.06 μM Compound: 4c	Antiproliferative activity against human Bel-7402 cells measured after 48 hrs by SRB assay Antiproliferative activity against human Bel-7402 cells measured after 48 hrs by SRB assay	[PMID: 32113125]
HepG2	IC₅₀	0.019 μM Compound: 4c	Antiproliferative activity against human HepG2 cells measured after 48 hrs by SRB assay Antiproliferative activity against human HepG2 cells measured after 48 hrs by SRB assay	[PMID: 32113125]
MCF7	IC₅₀	0.016 μM Compound: 4c	Antiproliferative activity against human MCF7 cells measured after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells measured after 48 hrs by SRB assay	[PMID: 32113125]

体内実験

Anticancer agent 62 (compound 4c) (BALB/c mice, 0-50 mg/kg, IP, once) inhibits human HepG2 xenograft mouse tumor growth by 71.7% at 25 mg/kg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2413148-58-8
分子量 537.39
分子式 C₂₀H₁₈N₃Na₂O₈PS
SMILES

COC1=NC(OC)=C(C=C1)NS(=O)(C2=CC3=C(N(C4=C3C=CC(OP(O[Na])(O[Na])=O)=C4)C)C=C2)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020 Apr 1;191:112181. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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