Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C20H12ClN3O5
- 分子量:409.78
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
5 μg/mL
Compound: 6xa
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 35487101] |
化学情報
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分子量 409.78
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分子式 C20H12ClN3O5
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SMILES
O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antitubercular agent-29 関連分類
HY-150554 関連分類
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