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Aprutumab

(別名: BAY 1179470)
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Based on 1 Customer Validation

Aprutumab (BAY 1179470) is a fully human fibroblast growth factor receptor 2 (FGFR2)-specific monoclonal antibody. Aprutumab induces FGFR2 endocytosis and degradation in cancer cells expressing FGFR2. Aprutumab serves as the targeted monoclonal antibody component of the antibody-drug conjugate BAY 1187982 (HY-141600) and mediates the endocytosis of the antibody-drug conjugate into FGFR2-positive cells. Aprutumab can be used for the research of FGFR2-positive solid tumors, including studies on gastric cancer and triple-negative breast cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.00%
  • CAS 番号: 1634620-63-5
  • 分子量:144.6 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Aprutumab
  • Experimental Validation Results for Aprutumab
  • Aprutumab Chemical Structure
    Aprutumab 構造式
CAS 番号: 1634620-63-5
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Aprutumab おすすめ製品:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    Human IgG1 lambda

  • 1/16

    Loaded Aprutumab on AHC2 biosensor, can bind FGFR-2 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78131) with an affinity constant of 1.819E-08 M as determined in BLI assay.

  • Aprutumab Chemical Structure
    1/16
  • Aprutumab
  • Loaded Aprutumab on AHC2 biosensor, can bind FGFR-2 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78131) with an affinity constant of 1.819E-08 M as determined in BLI assay.