Aumitin
Based on 1 Customer Validation
Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.78%
- CAS 番号: 946293-78-3
- 分子式: C24H20ClN5O
- 分子量:429.90
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Anti-Cancer Compound Library
HY-L025
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Autophagy Compound Library
HY-L029
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Cuproptosis Compound Library
HY-L133
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Cell Death Library
HY-L162
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
化学情報
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CAS 番号 946293-78-3
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性状 Solid
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分子量 429.90
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分子式 C24H20ClN5O
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Color White to off-white
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SMILES
O=C(NC1=CC=C(NC2=NC(NC3=CC=CC=C3)=CC(C)=N2)C=C1)C4=CC=CC=C4Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (232.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3261 mL | 11.6306 mL | 23.2612 mL | 58.1531 mL |
| 5 mM | 0.4652 mL | 2.3261 mL | 4.6522 mL | 11.6306 mL | |
| 10 mM | 0.2326 mL | 1.1631 mL | 2.3261 mL | 5.8153 mL | |
| 15 mM | 0.1551 mL | 0.7754 mL | 1.5507 mL | 3.8769 mL | |
| 20 mM | 0.1163 mL | 0.5815 mL | 1.1631 mL | 2.9077 mL | |
| 25 mM | 0.0930 mL | 0.4652 mL | 0.9304 mL | 2.3261 mL | |
| 30 mM | 0.0775 mL | 0.3877 mL | 0.7754 mL | 1.9384 mL | |
| 40 mM | 0.0582 mL | 0.2908 mL | 0.5815 mL | 1.4538 mL | |
| 50 mM | 0.0465 mL | 0.2326 mL | 0.4652 mL | 1.1631 mL | |
| 60 mM | 0.0388 mL | 0.1938 mL | 0.3877 mL | 0.9692 mL | |
| 80 mM | 0.0291 mL | 0.1454 mL | 0.2908 mL | 0.7269 mL | |
| 100 mM | 0.0233 mL | 0.1163 mL | 0.2326 mL | 0.5815 mL |
Aumitin 関連分類
HY-124726 関連分類
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