BAY-5000
Based on 1 Customer Validation
BAY-5000 (example 32) is a pyrimidinedione derivative. BAY-5000 can be used in the synthesis of cancer-related reagents.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.26%
- CAS 番号: 2639435-48-4
- 分子式: C22H14ClF3N2O3
- 分子量:446.81
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
1 μM
Compound: 36
|
Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
| MDA-MB-231 | IC50 |
874 nM
Compound: 36a; BAY-069
|
Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
化学情報
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CAS 番号 2639435-48-4
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性状 Solid
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分子量 446.81
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分子式 C22H14ClF3N2O3
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Color Off-white to light yellow
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SMILES
CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 250 mg/mL (559.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2381 mL | 11.1904 mL | 22.3809 mL | 55.9522 mL |
| 5 mM | 0.4476 mL | 2.2381 mL | 4.4762 mL | 11.1904 mL | |
| 10 mM | 0.2238 mL | 1.1190 mL | 2.2381 mL | 5.5952 mL | |
| 15 mM | 0.1492 mL | 0.7460 mL | 1.4921 mL | 3.7301 mL | |
| 20 mM | 0.1119 mL | 0.5595 mL | 1.1190 mL | 2.7976 mL | |
| 25 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2381 mL | |
| 30 mM | 0.0746 mL | 0.3730 mL | 0.7460 mL | 1.8651 mL | |
| 40 mM | 0.0560 mL | 0.2798 mL | 0.5595 mL | 1.3988 mL | |
| 50 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 60 mM | 0.0373 mL | 0.1865 mL | 0.3730 mL | 0.9325 mL | |
| 80 mM | 0.0280 mL | 0.1399 mL | 0.2798 mL | 0.6994 mL | |
| 100 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |